Chiral magnesium(II)-catalyzed asymmetric ring-opening of meso-aziridines with primary alcohols.
نویسندگان
چکیده
The asymmetric ring-opening of meso-aziridines with primary alcohols is realized using an N,N'-dioxide-Mg(OTf)2 complex as the catalyst. The desired vicinal trans-β-amino ethers are afforded in good yields and enantioselectivities. Aniline and water could also be used as the nucleophiles for the ring-opening in an identical catalyst system.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 50 شماره
صفحات -
تاریخ انتشار 2014